Orlando, the town of sunshine—and as of final week, the house of cutting-edge skincare. For a number of days, it reworked into the worldwide hub of dermatology, internet hosting the AAD Annual Assembly, the place science, innovation, and wonder got here collectively to redefine the way forward for skincare.
At ISDIN, we embrace this occasion with ardour: showcasing our newest launches, internet hosting business periods with famend specialists, and sharing a half-century of experience in solar safety. Alongside 1000’s of dermatologists from everywhere in the world, we explored the insights that may form self-care in 2025 and past.
For any skincare fanatic, that is the occasion of the 12 months. That’s why we’ve gathered the 5 key developments that stood out on the 2025 AAD Annual Assembly, bringing you insights straight from the professionals who skilled it firsthand.
What’s the AAD Annual Assembly?
Yearly, the American Academy of Dermatology (AAD) brings collectively main dermatologists, researchers, and skincare specialists from all over the world to debate the most recent in dermatology, aesthetics, and skincare know-how.
This 12 months, the occasion in Orlando was full of insightful discussions, groundbreaking analysis, and unique product launches. As leaders in solar safety and pores and skin well being, ISDIN was proud to be a part of this prestigious gathering, sharing our data and fascinating with the perfect within the subject.
Our sales space was a real illustration of our dedication to science-backed dermatology, efficacy, and innovation. “We had the prospect to showcase years of analysis, current our newest breakthroughs, and have interaction in significant discussions with prime dermatologists,” shares Alessandro De Luca, Medical Affairs Specialist.
Need to relive the thrill? Let our staff stroll you thru the occasion house on Instagram.
5 key skincare developments to know in 2025
From these three eventful days, we’ve distilled the 5 key skincare developments to pay attention to this 12 months. Able to get began?
1. A lesser-known acid takes the stage

Pigmentation stays a scorching matter in dermatology, and the AAD Annual Assembly put the highlight on tranexamic acid as a strong topical resolution.
Why is it so efficient? ISDIN Pre-clinical Supervisor Anthony Brown explains: “Tranexamic acid helps to scale back the looks of darkish spots by minimizing elements that contribute to melanin manufacturing.” Melanin is the pure pigment chargeable for bringing shade to your pores and skin.
As specialists mentioned our staff’s newest findings on pigmentation situations, they highlighted how tranexamic acid, mixed with niacinamide and different acids, can successfully goal uneven pores and skin tone. This analysis is on the coronary heart of our revolutionary Melaclear Superior serum, designed to ship a brighter, extra uniform complexion inside 12 weeks.

2. A highlight on photoaging

Greater than ever, specialists pressured the significance of stopping photoaging—the untimely indicators of pores and skin getting old attributable to solar publicity and environmental aggressors.
Alessandro explains, “Along with genetic or ‘pure’ getting old, photoaging is accelerated by exterior elements, resulting in wrinkles, solar spots, lack of elasticity, and, at occasions, mobile harm that may end up in extra severe situations.”
Skilled tricks to fight photoaging:
The excellent news? Photoaging may be prevented. That is the place day by day habits play a key position. Alessandro continues, “Prevention and safety from the solar’s dangerous results shouldn’t simply be a pattern—they need to be non-negotiable elements in our skincare routines.”
With that in thoughts, listed below are 5 important ideas*:*
- Sunscreen is your greatest ally: Intention to use it day-after-day, regardless of the climate. The golden rule of dermatologists? Reapply not less than each two hours.
- Nourish your pores and skin from inside: A weight-reduction plan wealthy in antioxidants like nutritional vitamins C and E helps fight free radicals and oxidative harm.
- Get high quality sleep and cut back stress: Relaxation and rest are important for pores and skin restoration and turnover.
- Hydrate, hydrate, hydrate: Consuming sufficient water and utilizing moisturizing merchandise strengthens the pores and skin and helps defend it from exterior aggressors.
- Consistency is essential: A morning and night routine is essential in serving to cut back the seen results of photoaging.
3. The following-generation retinoid

Among the many most talked-about substances at AAD was retinal (retinaldehyde), a potent but well-tolerated retinoid that’s famous to behave quicker than conventional retinol.
Martina Trabacchi, pharmacist and ISDIN Medical Affairs Specialist, explains, “Whereas retinol takes two steps to transform, retinal solely takes one—that means it converts into energetic kind extra rapidly.” It helps renew pores and skin, enhance texture, and cut back seen indicators of pores and skin getting old.
For those who’ve been interested in retinal, now’s the time to attempt it. Our dual-phase formulation, Retinal Superior, gives a focused resolution proven to scale back wrinkles by 43% after 4 weeks.*
4. A must have ingredient in nighttime skincare

One other key perception from the Annual Assembly was the rising give attention to melatonin as a game-changer in nighttime skincare. Dermatologists emphasised its highly effective position in supporting the pores and skin’s pure in a single day restore processes.
Lara Verdugo, ISDIN Advertising and marketing Supervisor, explains, “Melatonin has been clinically confirmed to assist stimulate pores and skin’s personal oblique defenses.” Science exhibits it’s a potent antioxidant that helps neutralize free radicals introduced on by day by day pores and skin stressors comparable to UV radiation and air pollution. In less complicated phrases, “You’re in a position to restore the harm of the day and likewise tackle all the stress that your pores and skin is subjected to the following,” continues Lara.
What else makes melatonin a rising star? It additionally enhances the pores and skin’s means to regenerate in a single day, making it a really perfect ingredient for well-aging formulation. “As we start to age, (the pores and skin’s) pure manufacturing of melatonin goes down—which suggests it must be supplemented,” Lara shares.
Right here’s the place melatonin skincare is available in. ISDIN is on the forefront of this pattern, and Melatonik® embodies our innovation. Combining melatonin, bakuchiol, and vitamin C, this serum-in-oil works whilst you relaxation, serving to to spice up the pores and skin’s pure defenses and restore a youthful look.
5. Past SPF—solar care that additionally repairs

Some of the thrilling conversations at AAD 2025 centered round solar care that goes past safety. Underneath the intense lights of the stage at our Business Session, world-renowned dermatologist Dr. Jean Krutmann revealed, “At present, we’ve the means and instruments to enhance the restore of UV-induced harm.”

That is the place DNA Repairsomes®, a key know-how in our bestselling sunscreens Eryfotona Actinica and Eryfotona Ageless, is available in. These merchandise do greater than defend the pores and skin from UV rays; they assist restore previous hurt from the solar.
Alessandro confirms: “Solar safety is important, however repairing the consequences of previous publicity is simply as essential. DNA Repairsomes® harness the ability of photolyase, an enzyme that aids in repairing sun-induced harm, serving to to take care of pores and skin well being over time.”
Solar care is evolving, and AAD 2025 made it clear: the way forward for sunscreen isn’t just about safety—it’s about restore.
What are the primary variations between Eryfotona Actinica and Eryfotona Ageless? Try the full information.
The way forward for skincare is right here

The 2025 AAD Annual Assembly reaffirmed that skincare is consistently evolving, pushed by new voices in scientific analysis. From highly effective substances like melatonin and retinal to groundbreaking solar safety and restore applied sciences, the business is concentrated on prevention, rejuvenation, and long-term pores and skin well being.
Now, it’s your flip. Incorporate these developments into your skincare routine, take heed to your pores and skin’s wants, and make prevention your primary technique. It’s by no means too late to start out—the steps you’re taking at this time result in the wholesome, glowing pores and skin you’ll take pleasure in tomorrow.
Reference:
*Analysis of effectiveness in 34 girls (41-70 years) with all pores and skin varieties with average to extreme photodamage throughout 84 days. Knowledge on file. ISDIN Corp., 2025. Morristown, NJ.
Amy is a content material strategist who turned a part-time obsession with skincare right into a full-time ardour. Her expertise as a inventive storyteller features a vary of way of life and know-how matters throughout Washington D.C. and Barcelona. What’s in her journey bag? Eye contour cream and sunscreen, at all times.